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Description
APC Mouse Anti-Human CD86 Antibody (S-3063)Product Specification Host Mouse Antigen CD86 Synonyms T lymphocyte activation antigen CD86; Activation B7 2 antigen; B70; BU63; CTLA 4 counter receptor B7. 2; FUN 1; CD28LG2 Location Cell membrane Accession P42081 Clone Number S 3063 Antibody Type Mouse mAb Isotype IgG2b,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation APC Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0.
Product Specification
| Host | Mouse |
| Antigen | CD86 |
| Synonyms | T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD28LG2 |
| Location | Cell membrane |
| Accession | P42081 |
| Clone Number | S-3063 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | APC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD86, also known as B7-2, is a co-stimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. It plays a crucial role in the immune response by interacting with CD28 on T cells to provide a necessary co-stimulatory signal for T cell activation, proliferation, and differentiation. Additionally, CD86 can also bind to CTLA-4, an inhibitory receptor on T cells, thereby regulating immune responses and maintaining immune homeostasis. This dual functionality makes CD86 a key target in immunotherapy research, particularly in the development of cancer treatments and autoimmune disease management strategies.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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4.6 ★★★★★
Based on 1705 reviews
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Product Reviews
★★★★★ 5
The most engaging interactive toy for my Border Collie
Color: Orange, Color: Orange
My Border Collie is not a big ball player. He prefers tug type games and actually gives me a look like, “Are you stupid? I’m not going to keep bringing that to you if all you’re going to do is throw it away again!” after about the third time I throw a ball for him to fetch. However, I can only play tug so often and I need him to be entertained and engaged as much as possible.
I got him a smaller, non-padded ball like this hoping he would like the interactive aspect of it. He did- he actually loved it! But it was loud, hard on his teeth, would come apart periodically, and he kept hitting the off button when playing with it. It drove me crazy. This one is so much better overall! The soft outer shell is not only easier on his teeth, but it is super resilient to biting and chewing. He actually likes to carry this thing around in his mouth while it’s bouncing and vibrating.
The three modes give great flexibility for different kinds of play. His favorite is the most active mode: the ball reacts to touch and practically bounces itself across the floor when he touches it with his paw or mouth. I will point out that in one of the modes, I thought the battery wasn’t charged or there was a motor issue because it’s very subdued movement; however, it’s just set up as a low-key option. Be sure to check out each mode to see which works best for your dog at different times.
I can’t say enough about this ball- I have been so pleasantly surprised by how much he loves it. The rechargeable feature is super convenient, it’s big enough to not get stuck under the couch, and it automatically shuts off based on whichever mode it’s set on. As the owner of a busy, super-smart dog who needs to be engaged in mental and physical activity, I think this all is worth every penny. In fact, I’m buying one for a friend who has a Border Collie pup with lots of energy to burn! I highly recommend this toy- it’s the most engaging toy I’ve found that Finn will play with on his own.
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Reviewed in the United States on April 13, 2026
★★★★★ 2
Not as Smart or Interactive as You Think it Will Be
Color: Blue
This is an honest review from a schnauzer owner who has has wanted this cheerble ball for their dog for more than one year. I finally bougI finally bought this toy and both me and my dog are disappointed. The settings are...i would say dog friendly as I'd assumed a dog ball would be. What I mean by that is, for example: the calm play setting is muuch too calm. Super light puffs of energy, like a battery is dying. And the playful setting is scary, alarmingly so. The intervals in between are too long. The ball does not bounce. So they just have settings all wrong. The size is good for a large dog only. Do not buy if you have a small to medium dog. I even think the material is okay. I've only had it for a few days so I can't even speak to how the material holds up. Really hoping to love this ball for my dog. It was not the distraction I was hoping it would be so I could work from home while my dog had fun. I'm hoping this can help someone else who's been pining over it. Essentially, it's a $35-$50 well made weighted ball that moves occasionally.
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Reviewed in the United States on May 9, 2026
★★★★★ 5
Great fun for our dogs!
Style: Original
My dogs can’t get enough of this very noisy ball. We have one outside and one in their playroom. It is very noisy. It is very hard. So, I’d say a room with fine furniture is not the place for it. Ours bang it around pretty good.
Our boxer did split one, biting it. But, she’s a serious chewer! Our other dog carries it around sometimes but hasn’t been able to damage it yet. So, I’d say for most chewers it’s going to last a long time.
It’s a great toy but in most households I’d say basement or outside. Again, it’s hard and did ding a few baseboards.
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Reviewed in the United States on March 27, 2026
★★★★★ 5
Superb!
Style: Original
My dog absolutely loves this ball. It's too big for him to fit all the way in his mouth, so it's held up pretty well and still makes the sounds.
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Reviewed in the United States on May 31, 2026
★★★★★ 4
Fun, but buy a couple of them
Style: Original, Style: Original
She loves them. Great toy, but the product can’t hold up- purchased 4-11-2026
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Reviewed in the United States on April 15, 2026