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Description
CD27 Mouse mAb (S-568-1)Product Specification Host Mouse Antigen CD27 Synonyms CD27L receptor, T cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, TNFRSF7 Immunogen Recombinant Protein Location Membrane Accession P26842 Clone Number 568 1 Antibody Type Mouse mAb Isotype IgG1,k Application WB, IHC P, ICC, FCM Reactivity Hu Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS,
Product Specification
| Host | Mouse |
| Antigen | CD27 |
| Synonyms | CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, TNFRSF7 |
| Immunogen | Recombinant Protein |
| Location | Membrane |
| Accession | P26842 |
| Clone Number | 568-1 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | WB, IHC-P, ICC, FCM |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC | 1:2000 | null |
| FCM | 1:2000 | null |
| ICC | 1:500 | null |
Background
Cluster of differentiation 27 (CD27) is a member of the tumor necrosis factor receptor superfamily and plays a key role in T-cell activation by providing a costimulatory signal. Bound to its natural ligand CD70, CD27 signaling enhances T-cell proliferation and differentiation to effector and memory T cells and therefore has potential as an immune modulatory target in cancer treatment [PMID: 32152062].
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